Extracellular Vesicles

What are extracellular vesicles? Extracellular vesicles (EVs) are small, membrane-bound particles which found in both eukaryotes (include animals, plants and protist) and prokaryotes (include bacteria and archaea).  They are present in biological fluids such as saliva, urine, breast milk and plasma. EVs are involved in multiple physiological and pathological processes.  EVs are like cell to…

EVs and Cancer

The sustained growth, invasion and development of secondary malignant growth of cancer cells at another site depends upon the cell-to-cell communication within our body. Such communication involves the released of extracellular vesicles by cancer cells and/or connective tissues cells which contain regulatory molecules that contribute to cell-to-cell communication within the tumour microenvironment. Extracellular vesicles carry…

Public Engagement

What is public engagement? Public engagement is a two-way process which the activity and benefits of higher education and research can be shared through the interactions with public. Public engagement provides opportunities for the public to get involved and to generate mutual benefits include gaining new insights, providing new perspectives, developing better research, and stimulate…

EVs and Cell Biology

Dr. Sarah Stewart is a fundamental cell biologist currently at the University of Cambridge. She has an interest in extracellular vesicles especially in how they are made and how they transfer their message into recipient cells, and what is important for cargo delivering into cells. Dr Stewart and her research team is trying to find…

EVs and Pregnancy

During pregnancy the mother immune system undergoes a lot of changes which help her tolerate the presence of foetus in the placenta in her body. One of the mechanisms for inducing the tolerance is thought to be the release of extracellular vesicles from the placenta into the circulation. Dr. Beth Holder is a lecturer in…

EVs and Graft-versus-host Disease

“I think public engagement explaining what we are doing to the general public, is a really good thing to start getting involved in just disseminating the work and putting on a level where people and patients can understand because at the end of the day the majority of our research is for the benefit of…

EVs and Atherosclerosis

“Public are curious and they want to find out more and increasingly that is becoming part of what we do is not doing the science behind close doors but hoping to engage the public and make them interested in what we do.” Dr. Charlotte Lawson Dr. Charlotte Lawson is a senior lecturer in comparative biomedical…

EVs and Motor Neurone Disease

“It is really important that the public is informed on what really is happening and how far we are moving along. On the other hand, it is also really important that the public inform and feedback to the scientists on what kind of research they would like to see because we might have a different…

EVs and Inflammation (Trauma & Burns)

Dr. Paul Harrison is a senior lecturer from the University of Birmingham, the Institute of Inflammation and Ageing.  He had been working in haematology since 1983 and have interested in extracellular vesicles since the 90s. At the moment he is based in the institute of inflammation and ageing which the laboratory is based in the…

EVs and Prostate Cancer

“EVs are bags that contain mysterious amount of objects or molecules that all have different functions and EV research is like down into the bag, pulling something out and trying to work out what it is.” Dr Victoria James Dr. Victoria James is an assistant professor in the University of Nottingham and she works on…